Nanoparticles in Cancer Therapy: Current Progress, Challenges, and Future Perspectives in Clinical Translation

  • Raghavendra Sashi Krishna Nagampalli Department of Immunology, St Jude Children’s Research Hospital, Memphis, TN 38105, USA
  • Eswar Kumar Nadendla Center of Advanced Study in Crystallography & Biophysics, University of Madras, Chennai- 600025, India
Keywords: Nanoparticles, Cancer therapy, Drug delivery, Nano chemotherapy, Multidrug resistance

Abstract

Cancer treatment is evolving with the advent of nanotechnology, shifting from conventional therapies to precision medicine. Nanoparticles (1–100 nm) which encapsulate drugs and direct them to tumor sites offer unique advantages in cancer therapy, including enhanced drug delivery, reduced toxicity, and improved specificity. This editorial examines various types of nanoparticles, with focus on those that have progressed to clinical trials, while addresses the challenges in translating these innovations from the laboratory to clinical practice. Despite the growing body of researNanoparticlesch, the number of approved nanodrugs remains limited. Hence a deeper understanding of nano formulations and their targeting mechanisms will be crucial to advancing cancer treatment in the future.

Published
2024-12-30