State-of-the-Art Approaches in Lung Cancer: Advancing Diagnosis, Treatment and Drug Discovery Through AI

  • Danish Mushtaq Post graduate Student, Department of Clinical Biochemistry, University of Kashmir, Srinagar, Jammu and Kashmir 190006, India
  • Harshita Bisht Post graduate Student, Department of MLT and Sciences, Delhi Pharmaceutical Sciences and Research University, Pushp Vihar, New Delhi 110017, India
  • Anam Beg Senior Project Associate, Department of Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India
  • Ashok Sharma Professor, Department of Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India.
  • Rashmi Gupta Department of Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India
Keywords: Lung cancer, SCLC, NSCLC, AI, Epigenetics, POTE

Abstract

Lung Cancer (LC) is one of the most common causes of cancer-related mortality worldwide, including India, with rising incidence attributed to smoking, air pollution and occupational exposures. It is broadly classified into Small Cell Lung Cancer (SCLC) and Non-Small Cell Lung Cancer (NSCLC), with very distinct pathological and therapeutic approaches. New developments and recent advances in diagnostic technologies, particularly AI tools are enhancing early diagnosis by allowing for faster assessments of radiological data such as genetic and environmental influences in terms of novel therapeutic opportunities. Immunotherapy and particularly checkpoint inhibitors, has improved survival with less toxicity. Integrative approaches involving ayurveda and homeopathy as alternative medicines are gaining more attention for curing the after effects of chemotherapy and radiotherapy. This review highlights current advancements in diagnosis and treatment strategies for LC, particularly focusing on the new molecular as well as alternative therapies in the context of Indian healthcare.

Published
2026-08-20