Unusual presentation of Erdheim-Chester disease complicated by severe hypercalcemia in a 25-year-old male: initial assessment and follow-up with 18 F-fluorodeoxyglucose-positron emission tomography and 3 Tesla MR imaging

Joseph Yu; Joshua Everhart; Hans Iwenofu

Unusual presentation of Erdheim-Chester disease complicated by severe hypercalcemia in a 25-year-old male: initial assessment and follow-up with 18 F-fluorodeoxyglucose-positron emission tomography and 3 Tesla MR imaging

Joseph Yu Ohio State University
Joshua Everhart Indiana University
Hans Iwenofu Ohio State University

Keywords: Erdheim-Chester; Histiocytosis; PET-CT; Osteosclerosis; Hypercalcemia

Abstract

We present a newly diagnosed case of Erdheim-Chester disease in a patient who presented with influenza-like symptoms, and whose course was complicated with life-threatening hypercalcemia. The imaging features were characteristic, and diagnosis was confirmed with immunohistochemical staining. The FDG-PET-CT was useful in diagnosis and follow-up.

Author Biographies

Joseph Yu, Ohio State University

Department of Radiology, Professor and Vice Chair

Joshua Everhart, Indiana University

Department of Orthopedic Surgery, Assistant Professor

Hans Iwenofu, Ohio State University

Department of Pathology, Associate Professor

Published

2021-07-30

Issue

Vol 1 No 1 (2021): Int J Radiol Case Rep

Section

Articles

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright © by the authors; licensee Research Lake International Inc., Canada. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution Non-Commercial License (CC BY-NC) (http://creative-commons.org/licenses/by-nc/4.0/).