Approaches Towards the Detection of Sepsis: A Review

  • Alice Heeroma Bangor University, United Kingdom
  • Jane Toffrey Xi'an Jiaotong-Liverpool University, China
  • Christopher David Gwenin Xi'an Jiaotong-Liverpool University, China
Keywords: Sepsis, Covid-19, Viral-based infections, Early diagnosis, Bacterial infection

Abstract

Our understanding of sepsis and its mechanisms have never been more important than they are today. In recent years we have seen sepsis manifest from bacterial infection to a broader range of pathogens, each with its unique responses from the body. This increased interest has only been further intensified by the Covid-19 pandemic and the renewed global attention towards viral-based infections and their interactions with sepsis. From Systemic inflammatory response syndrome (SIRS) to sequential organ failure assessment score (SOFA), studies have shown that early diagnosis is key, as well as finding the root of the infection to prevent further damage caused to the patient. Prompt treatment has contributed to the overall improvement of sepsis outcomes. This review summarizes the development of the cause, diagnosis, and treatments available to date.

Published
2021-02-26